Mexican men know the secret of the chili. It's about folate, a vitamin abundant in liver, leafy green vegetables, citrus fruits, sunflower seeds and legumes (beans and their relatives). It may sound more familiar to you that women of child-bearing age must have proper levels of folate (vitamin B9) in their diet for delivering healthy babies, but a new study published in the journal Human Reproduction and carried out by a team at the University of California, Berkeley, and the Lawrence Berkeley National Laboratory reveals that what the father eats counts too. And guess what? Folate levels in male diet appears to have the same importance. Low levels of this vitamin have been connected to sperm chromosomal abnormalities.
"Our study is the first to look at the effects of diet on chromosomal abnormalities in sperm. These abnormalities would cause either miscarriages or children with genetic syndromes if the sperm fertilized an egg," said co-author Suzanne Young, at UC Berkeley's School of Public Health.
Folate is required for the synthesis of DNA, RNA and proteins during cell division. It also controls the levels of homocysteine, an amino acid which can cause heart issues when overcoming a certain threshold.
Low levels of folate in women just before and during pregnancy (less than 400 mg daily) has been connected to greatly increased risk of embryos developing neural tube malformations, like spina bifida or anencephaly (undeveloped brain). Many countries (US started from 1998) require the addition of folate to breads, cereals and other grain products. Follow-ups connected this measure with a drop in the cases of neural tube birth defects.
Sperm health and diet
1 to 4 % of a healthy male's sperm displays abnormal chromosome numbers (aneuploidy), a result of defective meiosis. Eggs fertilized by such a sperm develop into an embryo prone to miscarriage or a fetus with aneuploidy, translated to severe conditions (for example, an extra chromosome 21 is the cause of Down syndrome while an extra X chromosome in boys triggers Klinefelter syndrome).
The research was made on a poll of 97 men, aged 22 to 80, current or ex-employees of a government research laboratory. The subjects were chosen after excluding smokers and subjects with already known fertility issues. Questionnaires assessed average intake of dietary and supplemental nutrients. One week later, semen samples were collected. The team considered factors like age, alcohol use and medical history.
Subjects having the highest consume of folate had 19 % less aneuploid sperm cells than those with moderate folate consume, and 20 % lower rates compared to subjects consuming low levels of folate.
"Increasing folate intake can be as simple as taking a vitamin supplement with at least 400 micrograms of folate or eating breakfast cereal fortified with 100% of the RDA [recommended daily intake] for folic acid. In addition, green leafy vegetables, such as spinach, can have up to 100 micrograms of folate per serving," said Young.
Various nutrients in the diet were taken into account.
"The results of the different analyses were different, which gave us some confidence that we could look at the effect of these micronutrients separately. The definitive way to answer this question would be with a randomized control trial with folate supplementation," said Young.
The team did not find a connection between sperm aneuploidy and the other nutrients, like zinc, calcium, beta-carotene and other vitamins. Researchers warn that momentarily this is just a connection, as the cause-and-effect relationship has not been investigated.
"We did come up with enough evidence to justify a larger, clinical and pharmacological trial in men to examine the causal relationships between dietary folate levels and chromosomal abnormalities in their sperm. This information will help us set dietary folate levels that may reduce the risk of miscarriage or birth defects linked to the fathers," said lead researcher Andrew Wyrobek, chair of the Radiation Biosciences Department at Lawrence Berkeley National Laboratory.
So, did you get your daily 400 mg of folate?
Source: news.softpedia.com
Vitamins and Healthy Sperm
The Fattest Man on the Planet: 560 kg (1,244 pounds)
Guinness World Records is going to register him. Mexican Manuel Uribe had reached 560 kilos (1,244 pounds) weight but has already lost 200 kilos (444 pounds) because of the Zone diet. Uribe wants to also break the record for drastic slimming.
"I'm happy to be included in the Guinness World Records as the fattest man on the planet. I'm also happy that I have managed slimming 200 kg", said Uribe, now aged 42.
He lives in Monterrey (northern Mexico). It is reported that Guinness authorities have informed him that he will be on the 2008 edition of the Records Book and on the 2009 one for the most incredible weight loss in a year (200 kilograms). He celebrated the event, managing to go out of the house aboard a trailer. Guinness offered him for his weight performance a glass plaque.
His photograph is included in the 2008 Guinness Book of Records alongside a description of the treatment he has had and offers of surgery he has received so far.
Uribe has been suffering from obesity for 20 years. At 20 years, he was working in US and weighed 130 kg (289 pounds) at a height of 1.95 m. He looked for medical help in 2006, when he reached 560 kilograms. Uribe appeared then on a TV channel asking to be helped to escape excess weight that kept him captive in the house for almost 20 years.
For the moment, Uribe cannot move by himself and lives immobilized on bed, his mother taking care of him. At 362 kg (800 lbs), Uribe is still morbidly obese but in March 2007 he set a goal: to slim till 120 kg (254 pounds).
Uribe's weight history:
1966 - Birth weight 6lbs (2.7 kg)
1984 - (18) 121 kg (19 stone)
1988 - (22) 128 kg (20 stone)
1995 - (29) 245 kg (39 stone)
1999 - (33) 502 kg (79 stone)
2000 - (34) 552 kg (87 stone)
Previous Diet
Breakfast - 4 eggs, beans, 3-4 tortillas stuffed with cheese and meat, fizzy drinks, coffee, milk
Lunch - Half a chicken, 4 meat and cheese tortillas, salad, fizzy drinks, pasta, bread
Dinner - 3-4 eggs with ham, beans, 3-4 cheese and meat tortillas, bread or pasta, fizzy drinks, coffee, milk
Current Diet
Breakfast - Six eggs without yolk fried in olive oil, onion and tomato, one apple, one grapefruit, water
Lunch - Grilled chicken, grapefruit, apple, sugar-free lemonade, salad, sugar-free jelly, water
Dinner - Peppers stuffed with mince, one apple, grapefruit, salad, water
Snack - 2.5 bars of diet chocolate, water
Source: news.softpedia.com
The Health Benefits of Yogurt
Yogurt is one of the most versatile types of food out there
Yogurt has become such an integral part of our diets that we've grown used to taking its beneficial effects for granted, without asking too many questions with regard to its contents or the finer details of its inner workings. For the more yogurt-curious among you, here is a short guide to the many health benefits of this familiar product, which has practically taken over the dairy aisle at most modern supermarkets.
Yogurt is of course made from milk, which means that it contains animal proteins (about 9 grams per 6-ounce serving, nutritionists say). It also contains a lot of calcium, vitamin B-2 and B-12, as well as potassium and magnesium. However, the one key component of yogurt which has made the headlines more and more over the past years is something generically known as "probiotics". Experts say probiotics are in fact "friendly bacteria", which occur naturally in the digestive system and many yogurt products contain live strains of these "good bacteria", which studies indicate can help boost the immune system and contribute to the overall health of the digestive tract.
There are still not enough studies to turn these assumptions into hard facts, but scientists have many reasons to believe that yogurt with active cultures may help certain gastrointestinal conditions, including constipation, diarrhea, colon cancer and inflammatory bowel disease. The benefits are believed to come from the fact that yogurt changes the microflora in the intestines, as well as the time food takes to go through the bowel. Also, as mentioned before, certain probiotic strains enhance the body's immune system, boost resistance to and recovery from infection, and improve the success of drug therapy.
Finally, yogurt contains a lot of calcium and vitamin D, which experts say helps fight the most common type of bone diseases - osteoporosis. "The combination of calcium and vitamin D has a clear skeletal benefit, provided the dose of vitamin D is sufficiently high," explains Jeri Nieves, director of bone density testing at New York’s Helen Hayes Hospital. As a result, many of the currently available brands of yogurt with added vitamin D can prove an excellent companion in the fight for the prevention of osteoporosis, particularly for older people. The conclusion is simple: yogurt should not be missing from your diets, and you'll learn to appreciate both its immediate and its long-term benefits.
Source: news.softpedia.com
Grapefruit Juice - Drug Interactions
Fenomenon Diet of the 80s
In 80s, we can say that if you wanted guaranteed weight loss, the grapefruit diet was the plan to follow. Providing no more than 800 calories a day, the grapefruit diet menu involved eating lots of 'fat-burning' grapefruit to kick-start your metabolism. It same as much black coffee as you liked, some daily protein (mainly boiled eggs) and the odd piece of dry toast.
At the time, nutrition experts dismissed it as another fad diet. They explaining that the 'fat-burning' properties of grapefruit were, in fact, a myth and any weight loss that occurred was due to the extremely low and potentially dangerous calorie intake.
The Warning
But two decades on, it seems these nutritionists may need to rethink their views on the popularity of grapefruit as a 'diet food' if the results of a study published earlier this year to be believed. The latest research, the simple act of adding grapefruit and grapefruit juice to your diet, really can aid weight loss. But unlike the seriously restricted diet of the 80s, you get these results without changing what else you eat.
While this research might tempt you to fill up on grapefruit to boost your weight loss campaign, if you’re taking any medications you might want to speak to your GP first or check the literature that comes with your medication.
This is because a wealth of research shows that grapefruit juice can interact with a number of medications, potentially causing serious side effects. It works by inhibiting an enzyme in the intestines that’s responsible for the natural breakdown and absorption of many medications. When the action of this enzyme is blocked, blood levels of these medications increase and this can lead to potentially toxic side effects.
Research suggests that flavonoids and/or furanocoumarin compounds are the substances in grapefruit juice that block the enzyme in the intestines. Many drugs appear to be affected by grapefruit juice so if you are taking any medication, it’s essential to check whether you can safely consume grapefruit juice. In the meantime, it’s likely that grapefruit segments may also interact with certain medications so you’d be wise to consult your GP before eating lots of grapefruit. Other citrus fruits don’t seem to have any effect.
The Research
Grapefruit juice provides many nutrients, such as vitamin C and lycopene. But chemicals in grapefruit interfere with the enzymes that break down (metabolize) certain drugs in your digestive system. This can result in excessively high levels of these drugs in your blood and an increased risk of serious side effects.
The exact chemicals in grapefruit juice that cause this interaction aren't known. But these chemicals are present in the pulp and peel of grapefruit as well as in the juice. For this reason, any grapefruit products can interact with certain medications. Include dietary supplements that contain grapefruit bioflavonoids. If you avoid grapefruit, you may also want to avoid tangelos, a hybrid grapefruit, and Seville oranges, a type of bitter orange often used to make marmalade and compotes. They may have a similar effect.
The study included 100 obese people who were divided into three groups. The first group ate half a grapefruit before each meal three times a day. The second group drank grapefruit juice before each meal. The third group received no grapefruit. No other changes were made to their diets.
After 12 weeks, those participants who ate grapefruit with each meal lost, on average 3.6lb. Only a third of a pound a week, but pretty good considering they didn't make any other changes to their diet. Meanwhile, those who drank grapefruit juice three times a day lost 3.3lb in the 12 weeks. By comparison, the grapefruit-free participants lost, on average, only 0.5lb.
But weight loss wasn't the only health benefit seen when grapefruit or the juice was consumed. The research also found the grapefruit-consuming participants had lower levels of insulin, a hormone that regulates blood sugar levels and fat metabolism, which in turn might help to reduce the risk of diabetes or stroke.
The Theory
The researchers believe grapefruit contains unique plant compounds that reduce insulin levels, which in turn promotes weight loss.
The link between raised insulin levels and excess weight is complicated and multifaceted. To start with, high levels of insulin may indicate that sugar isn't efficiently utilised for energy with the result that it's more likely to be stored as fat. Secondly, high levels of insulin can make people feel hungry so that they eat more. And finally, high levels of insulin prevent the body from breaking down fat. Add these together, and it's easy to see why lower levels of insulin may promote weight loss. What exactly it is in grapefruit that has this insulin-lowering effect remains unclear.
Care needs to be taken when interpreting the results. It's the first study of it's kind and even the researchers believe more work needs to be carried out before recommendations are made regarding grapefruit intake. Fortunately, a larger study is already planned for later this year.
When it comes to reducing the risk of diabetes, experts also believe we should err on the side of caution before recommending vast amounts of grapefruit.
Nutrition experts also agree that more research is needed before rushing out to stock up on grapefruit. Most tend to agree with the nutritionalists of the 80s and say it's unlikely that grapefruit has any magical properties in terms of aiding weight loss in the absence of other diet or lifestyle changes. It's perhaps more likely that participant’s lost weight simply because they were taking part in a study and, as a result, were more focussed on their food intake and exercise habits.
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